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Special Challenges In Comparative Effectiveness Research On Children's And Adolescents' Health

October 2010

Health Affairs 29(10): 1849-1856
Lewin Contact: Cliff Goodman

This article on CER that targets Child and Adolescent Health was published in a special CER-focused issue by Health Affairs. The article details how CER needs to be targeted, designed, conducted, and reported in ways that are responsive to the unique circumstances of children and adolescents

Expertise Area: Children, Youth, and Family Policy, Comparative Effectiveness Research, Evidence-Based Medicine / HTA


Using Electronic Health Data to Support Effectiveness Research and Medical Product Safety

February 2010

Lewin Contact: Cliff Goodman

A presentation at the Health IT Summit for Government Leaders conference on use of EHR to support CER and Medical Product Safety programs.

Expertise Area: Comparative Effectiveness Research


Laboratory Medicine and Comparative Effectiveness Research

January 2010

Lewin Contact: Cliff Goodman

Comparative effectiveness research (CER) is reshaping the evaluation of health care technology in the United States, with implications for innovation, regulation, payment, access, quality, and costs. The interest in CER arises from a widely perceived shortfall in evidence to inform decisions by clinicians, patients, health care provider organizations, and payers. The evidence expectations inherent in CER offer distinct challenges to the laboratory sector, as well as opportunities for those that can demonstrate the value of laboratory tests in the CER paradigm. 

This report explains the rationale for CER, what CER is, and its significance for laboratory medicine. It describes the types of evidence generated by CER and how it compares with the evidence usually generated for regulatory purposes. The report summarizes current federal activities in CER that are relevant to laboratory medicine. Further, it describes implications of CER for the laboratory testing sector.

Client Area: Associations
Expertise Area: Comparative Effectiveness Research


Comparative Effectiveness Research and Personalized Medicine: From Contradiction to Synergy

October 2009

Lewin Contact: Cliff Goodman

The Lewin Group Center for Comparative Effectiveness Research released a report prepared for the Personalized Medicine Coalition describing how comparative effectiveness research (CER) can be designed, conducted, and reported to better align with personalized medicine, achieving a synergy toward improved patient outcomes.  While CER has been oriented largely toward evaluating treatment effects across study populations, personalized medicine focuses on using individuals’ genomic information and other personal traits to inform decisions about their health care.  It is essential that these emerging initiatives evolve to complement, not contradict, each other. 

Expertise Area: Comparative Effectiveness Research


The Value of Laboratory Screening and Diagnostic Tests for Prevention and Health Care Improvement

September 2009

The paper is located here. The other link provides you a link to the web page for the conference and other materials.
Lewin Contact: Cliff Goodman


Client Area: Associations
Expertise Area: Comparative Effectiveness Research

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